性能参数
产品名称: FITC标记的MS4A15蛋白抗体
英文名称: Anti-MS4A15/FITC
抗体货号: HZ-13691R-FITC
产品规格: 100ul
级 别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价 格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种:
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2020/11/23 13:35:00
详细资料:
实验方法技术资料
浏览人数:245
供应商: 上海沪震实业有限公司
诚信指数:13682点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。
产品详细描述
Rabbit Anti-MS4A15/FITC Conjugated antibody
FITC标记的MS4A15蛋白抗体
英文名称 | Anti-MS4A15/FITC |
中文名称 | FITC标记的MS4A15蛋白抗体 |
别 名 | FLJ34527; Hypothetical protein MGC35295; M4A15_HUMAN; Membrane spanning 4 domains subfamily A member 15; Membrane-spanning 4-domains subfamily A member 15; MGC35295; MS4A15. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 跨膜蛋白 细胞膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 25kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MS4A15 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: MS4A (membrane-spanning 4-domain family, subfamily A) is a large family of proteins that includes at least 26 members in mouse and humans. Flanked by amino- and carboxyl- cytoplasmic regions, MS4A family members contain four highly conserved transmembrane domains. CD20, the most well-known MS4A family member, is a B-cell-specific molecule that functions as a calcium-permeable cation channel and is known to accelerate the G0 to G1 progression induced by IGF-1. MS4A15 (membrane-spanning 4-domains, subfamily A, member 15) is a 240 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding MS4A15 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: May be involved in signal transduction as a component of a multimeric receptor complex. Subcellular Location: Membrane. Similarity: Belongs to the MS4A family. Database links: Entrez Gene: 219995 Human Entrez Gene: 545279 Mouse SwissProt: Q8N5U1 Human SwissProt: Q3UPL6 Mouse Unigene: 207465 Human Unigene: 329729 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
MS4A(跨膜4结构域家族,A亚家族)是蛋白质的大家族,在小鼠和人类中至少包括26个成员。Ms4A家族成员由氨基酸和羧基细胞质区域组成,共含有四个高度保守的跨膜结构域。CD20是最著名的MS4A家族成员,是一种B细胞特异性分子,其作用是钙渗透性阳离子通道,并已知可加速IGF-1诱导的G0至G1的进展。MS4A15(跨膜4结构域,亚家族A,成员15)是一种240个氨基酸的多路膜蛋白,以两种可选择的剪接异构体存在。编码MS4A15的基因映射到人类第11号染色体,该基因含有1400个以上的基因,并包含人类基因组的近4%。Jervell和Lange-Nielsen综合征、Jac.n综合征、Niemann-Pick病、遗传性血管水肿和Smith-Lemli-Opitz综合征与映射到11号染色体的基因缺陷有关。
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。
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