FITC标记的皮肤桥蛋白抗体
产品名称: FITC标记的皮肤桥蛋白抗体
英文名称: Anti-Dermatopontin/FITC
产品编号: HZ-14282R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-Dermatopontin/FITC Conjugated antibody
FITC标记的皮肤桥蛋白抗体
英文名称 | Anti-Dermatopontin/FITC |
中文名称 | FITC标记的皮肤桥蛋白抗体 |
别 名 | DERM_HUMAN; Dermatopontin; Dpt; TRAMP; Tyrosine rich acidic matrix protein; Tyrosine-rich acidic matrix protein. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 信号转导 细胞骨架 细胞外基质 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 24kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Dermatopontin |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq, Jul 2008] Function: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation. Subcellular Location: Secreted > extracellular space > extracellular matrix. Tissue Specificity: Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts. Post-translational modifications: Sulfated on tyrosine residue(s). Similarity: Belongs to the dermatopontin family. Database links: Entrez Gene: 1805 Human Omim: 125597 Human SwissProt: Q07507 Human Unigene: 80552 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Dermatopontin是一种细胞外基质蛋白,可能在细胞基质相互作用和基质组装中发挥作用。蛋白质在多种组织中发现,许多酪氨酸残基都是硫酸化的。Dermatopontin被假定为通过与核心蛋白聚糖的相互作用来改变TGF-β的行为。[ RefSeq,JUL 2008 ]