Anti-ZNHIT2抗体
产品名称: Anti-ZNHIT2抗体
英文名称: ZNHIT2
产品编号: YB--16415R
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
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- 邮编 : 200612
- 所在区域 : 上海
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- 传真 : 021-60514606
- 邮箱 : shybio@126.com
Anti-ZNHIT2抗体
产品编号 | YB-16415R |
英文名称 | ZNHIT2 |
中文名称 | ZNHIT2蛋白抗体 |
别 名 | C11orf5; FON; MGC120285; MGC120286; OTTHUMP00000230419; Protein FON; Zinc finger HIT domain-containing protein 2; Zinc finger HIT type containing 2; zinc finger, HIT domain containing 2; zinc finger, HIT type 2; ZNHI2_HUMAN; ZNHIT2. |
规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 细胞生物 转录调节因子 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, |
产品应用 | WB=1:500-2000 ELISA=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 45kDa |
细胞定位 | 细胞核 细胞浆 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZNHIT2:51-150/403 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: ZNHIT2 (zinc finger, HIT-type containing 2), also known as FON, is a 403 amino acid protein that is highly expressed in the seminiferous tubules of testis, with low expression in other tissues. Containing one HIT-type zinc finger, ZNHIT2 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. Tissue Specificity: Low expression in most tissues; highly expressed in testis. Similarity: Contains 1 HIT-type zinc finger. SWISS: Q9UHR6 Gene ID: 741 Database links: Entrez Gene: 741 Human Entrez Gene: 539138 Cow Entrez Gene: 100514699 Pig Entrez Gene: 309177 Rat Omim: 604575 Human SwissProt: Q2TBW5 Cow SwissProt: Q9UHR6 Human Unigene: 41757 Cow Unigene: 121025 Human Unigene: 19362 Pig Unigene: 18470 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品图片 |
Protein: bladder(mouse) lysates at 40ug;
Primary: Rabbit Anti-ZNHIT2 (bs-16415R) at 1:300; Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000; Predicted band size:45 kD Observed band size:45 kD |