Anti-CSPP1抗体
产品名称: Anti-CSPP1抗体
英文名称: CSPP1
产品编号: YB--9208R
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
- 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 183****2235
- 传真 : 021-60514606
- 邮箱 : shybio@126.com
Anti-CSPP1抗体
产品编号 | YB-9208R |
英文名称 | CSPP1 |
中文名称 | 中心体和纺锤体极相关蛋白1抗体 |
别 名 | Centrosome and spindle pole associated protein 1; CSPP 1; CSPP; FLJ22490; FLJ38886; CSPP1_HUMAN. |
规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Cow, Horse, Sheep, |
产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 146kDa |
细胞定位 | 细胞浆 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CSPP1:151-250/1256 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: Centrosomes are dynamic organelles involved in many aspects of cell function and growth. Centrosomes act as microtubule organizing centers, and provide a site for concerted regulation of cell cycle progression. Duplication of centrosomes occurs once during each cell cycle and requires proper mitotic spindle formation and chromosome segregation. Defects in centrosome duplication or function are linked to many human diseases, including various forms of cancer. The centrosome and spindle pole-associated protein 1 (CSPP1) interacts with centrosomes and microtubules and may play a role in the regulation of G(1)/S-phase progression and spindle assembly. Two isoforms of CSPP1 exist as a result of alternative splicing events. Isoform 1 expression increases throughout the cell cycle and peaks in G2/M phase, whereas isoform 2 expression is highest in G1 phase and decreases thereafter. Function: May play a role in cell-cycle-dependent microtubule organization. Subunit: Interacts with PLEKHG6 Subcellular Location: Cytoplasm; cytoskeleton; centrosome. Cytoplasm; cytoskeleton; spindle. Note: Associated with mitotic spindles. Tissue Specificity: Detected in testis. Post-translational modifications: Phosphorylated. Phosphorylation increases in colcemide-treated cells. SWISS: Q1MSJ5 Gene ID: 79848 Database links: Entrez Gene: 79848 Human Omim: 611654 Human SwissProt: Q1MSJ5 Human Unigene: 370147 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |