性能参数
产品名称: API3;BIRC4;hIAP-3;hIAP3;IAP-3;ILP1;MIHA;XLP2
英文名称: Anti-XIAP Polyclonal Antibody
抗体货号: K106527P
产品规格: 100ul
级 别: WB 1:3000.
产品产地: 北京
品牌商标: Solarbio
价 格: 1600元
抗原: A synthetic peptide of human XIAP
抗原来源:
抗体来源: Rabbit
适用物种: Human Mouse Rat
Isotype:IgG
应用范围: WB
更新时间: 2020/6/13 12:54:00
详细资料:
实验方法技术资料
浏览人数:388
供应商: 北京索莱宝科技有限公司--实验室产品
诚信指数:579点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。
产品详细描述
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。
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