Anti-Heme Oxygenase 1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Heme Oxygenase 1/FITC Conjugated抗体

Anti-Heme Oxygenase 1/FITC Conjugated抗体

商家询价

产品名称: Anti-Heme Oxygenase 1/FITC Conjugated抗体

英文名称: Anti-Heme Oxygenase 1 /FITC

产品编号: YB--23667R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-Heme Oxygenase 1/FITC Conjugated抗体

产品编号 YB-23667R-FITC
英文名称 Anti-Heme Oxygenase 1 /FITC
中文名称 FITC标记的 血红素氧合酶 1/热休克蛋白32抗体
别    名 Heme oxygenase (decycling) 1; Heme oxygenase 1; Hemox; HMOX 1; Hmox; HMOX1; HO 1; HO-1; HO; HO1; Hsp32; bK286B10; D8Wsu38e; HMOX1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  免疫学  神经生物学  信号转导  表观遗传学  Alzheimer's  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Heme Oxygenase 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The hemeoxygenase-1 calls that the hemoglobin oxidizes to synthesize the enzyme again-1( hemeoxygenase-1, HO-1) is the catalyst enzyme that a kind of hemoglobin declines the solution, under the NADPH and the cell dye P-450 revivification enzymes and the member oxygen functions, the catalyst HO-1 hemoglobin declines the solution as the courage green vegetable, CO and irons, the former revivification has the very strong anti- to oxidize the ability after become the red vegetable of courage , the latter is a kind of important letter to make the member.

Function:
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. 

Subcellular Location:
Microsome. Endoplasmic reticulum. 

Tissue Specificity:
Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). 

DISEASE:
Defects in HMOX1 are the cause of heme oxygenase 1 deficiency (HMOX1D) [MIM:614034]. A disease characterized by impaired stress hematopoiesis, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues. Clinical features include persistent hemolytic anemia, asplenia, nephritis, generalized erythematous rash, growth retardation and hepatomegaly. 

Similarity:
Belongs to the heme oxygenase family. 

Database links:

Entrez Gene: 442987 Dog

Entrez Gene: 3162 Human

Entrez Gene: 15368 Mouse

Entrez Gene: 24451 Rat

Omim: 141250 Human

SwissProt: Q5E9F2 Cow

SwissProt: P09601 Human

SwissProt: P14901 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications