Anti-AMACR(C-term) Monoclonal Antibody

英文名称	Anti-AMACR(C-term) Monoclonal Antibody
宿主	Mouse
别名	AMACRD;CBAS4;P504S;RACE;RM
应用	WB ICC
稀释比例	WB 1:1000. ICC 1:100.
交叉反应	Rat
蛋白分子量	42kDa
Gene ID	23600
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human AMACR(C-terminus) protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human AMACR(C-terminus) protein fragments expressed in E.coli.
Subcellular Locations	Mitochondrion Peroxisome
Swiss Prot	Q9UHK6
克隆号	2F3-C11-B12
克隆类型	Monoclonal Antibody
背景资料	This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.