Albumin & IgG Depletion SpinTrap

Albumin & IgG Depletion SpinTrap are prepacked columns for the depletion of albumin and IgG from human serum and plasma. They are prepacked with high performance SepharoseTM based media with an affinity for human serum albumin (HSA) and IgG

• Albumin & IgG Depletion SpinTrap is a prepacked column for the depletion of albumin and IgG from human serum or plasma.
• Albumin & IgG Depletion SpinTrap handles smaller sample volumes (~50 μl) using a tabletop centrifuge.
• Columns are prepacked with high performance Sepharose based media with an affinity for human serum albumin (HSA) and IgG.
• High depletion capacity, removes > 95% HSA and > 90% IgG, with high reproducibility.
• Simple and fast procedure.
• Removal of albumin and IgG allows a higher load of less abundant proteins to be included in the analysis and detection of more proteins.

Albumin & IgG Depletion SpinTrap and HiTrap Albumin & IgG Depletion are prepacked columns for the depletion of albumin and IgG from plasma and serum samples. Albumin and IgG are the most abundant plasma proteins, and they tend to obscure the signals of less abundant proteins. Depletion of the two proteins removes more than 60% of the total protein content in human plasma, allowing a higher load of less abundant proteins to be included in the analysis and detection of more proteins. These columns are members of the Trap platform and address the need for flexible, small-scale preparation of protein samples prior to downstream analyses such as 1-D or 2-D gel electrophoresis and mass spectrometry.