【Webinar预告】如何使用器官芯片技术构建更真实的体外环境?欢迎围观-Molecular Devices

来源: 美谷分子仪器(上海)有限公司   2019-4-4   访问量:1396评论(0)

如何使用器官芯片技术构建更真实的体外环境?




器官芯片(Organ-on-a-Chip)技术是一种新型的药物检测技术。该技术通过结合微流控技术提高传统细胞培养的生理相关性。芯片上的器官是3D组织,可以更好地体现出体内组织的复杂性,包括3D形态、细胞外基质嵌入、多种细胞类型、血管结构和灌流。





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本次课堂重点介绍内容:
● 复杂的3D组织的培养和成型
● 探索生命科学奥秘的高内涵成像解决方案

主讲人简介

In this presentation I will introduce culture and interrogation of complex 3D tissues, such as liver, kidney, gut and brain tissue. The tissues are grown on the OrganoPlate® platform, that allow culturing of over 40 tissues in parallel. The tissues are embedded in an extracellular matrix gel and comprise both stromal tissue, bloodvessel structures as well as epithelial barriers with clear apical and basal sides. The platform can be interrogated using automated imaging equipment as well as all standard equipment including fluorescence-based assays, immunohistochemical staining, barrier integrity monitoring, transport studies, viability assays, qRT-PCR, ELISA’s and many others. Last but not least, operation of the platform is thus straightforward that an end-user who is not necessarily an expert in the field of microfluidics is able to perform the study. In this presentation I will show examples of Organ-on-a-Chip tissues for use in drug safety testing and disease modelling.

此部分中,来自Molecular Devices公司的高级产品经理艾平将带来的关于“探索生命科学奥秘的高内涵成像解决方案”的介绍。重点介绍高内涵概念、在基于细胞成像的生命科学研究以及药物筛选和毒性安全评价中的应用、以及Molecular Devices提供的高内涵成像分析解决方案。






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