Anti-Active Rab11 Mouse Monoclonal Antibody
产品名称： Anti-Active Rab11 Mouse Monoclonal Antibody
英文名称： Anti-Active Rab11 Mouse Monoclonal Antibody
产品编号： 26919
产品价格： null
产品产地： 美国
品牌商标： NewEastbio
更新时间： null
使用范围： IP, IHC
武汉纽斯特生物技术有限公司
- 联系人 :
- 地址 : 武汉市东湖新技术开发区光谷生物城B3-3栋2-3楼
- 邮编 : 430074
- 所在区域 : 湖北
- 电话 : 186****7297
- 传真 : 027-87561022
- 邮箱 : neweast3@126.com
| Catalog Number: 26919 |
| Gene Symbol: RAB11 |
| Description: Anti-Active Rab11 Mouse Monoclonal Antibody |
| Background: Small GTPases of the Rab-family are crucial elements of the machinery that controls membrane traffic. Rab11 has been shown to control traffic through the recycling endosome. |
| Immunogen: Recombinant full length protein of active Rab11 |
| Applications: IP, IHC |
| Recommended Dilutions: IP: 1 μg for 1~2 mg total cellular proteins IHC: 1:50~100 dilution |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG2b |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-active Rab11 antibody recognizes active Rab11 from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Immunoprecipitation/Western blot: |
 |
Purified full-length Rab11 proteins were immunoprecipitated after treated with GDP (lane left) or GTPγS (lane right). Immunoprecipitation was done with the anti-active Rab11 monoclonal antibody (Cat. No. 26919). Immunoblot was with an anti-Rab5 polyclonal antibody (Cat. No. 21157). |
| Publications: |
| 1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors Hepatology Volume 61, Issue 1, pages 361–374, January 2015 |
| 2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance Endocrinology. 2014 Sep;155(9):3315-28 |