分子量:42.4 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human Fetuin B, His Tag by the LAL method.

Buffer:50 mM Tris, 150 mM NaCl,pH8.0

生物活性:

产品特性:Human Fetuin B, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 42.4 kDa. The predicted N-terminus is Cys 16. The reducing (R) protein migrates as 48-60 kDa in SDS-PAGE  due to glycosylation.

产品背景:Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liver-derived plasma protein, FETUB is essential for fertilization.