HTRA2 抗体-第二抗体-抗体-生物在线
HTRA2 抗体

HTRA2 抗体

商家询价

产品名称： HTRA2 抗体

英文名称： HTRA2 Antibody

产品编号： XY15775-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 HTRA2 抗体

Applications
Tested Applications: ELISA, WB, IHC, IP
Cited applications IF
Specificity Reaction: Human,Mouse,Rat, Monkey; Other species are not tested.Please decide the specificity by homology
Cited species Human, mouse
Positive WB detected in HEK-293 cells, COS-7 cells, HeLa cells, human heart tissue, Jurkat cells, MCF7 cells, mouse skeletal muscle tissue, Raji cells
Positive IP detected in Raji cells
Positive IHC detected in Human kidney tissue, human colon tissue, human thyroid tissue
Recommended dilution WB : 1:1000-1:10000
IP : 1:200-1:2000
IHC : 1:20-1:200
 HTRA2 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12NextView more validation data
  • 15775-1-AP;HEK-293 cellsHEK-293 cells were subjected to SDS PAGE followed by western blot with 15775-1-AP(HTRA2 antibody) at dilution of 1:2000
  • 15775-1-AP;human kidneyImmunohistochemical of paraffin-embedded human kidney using 15775-1-AP(HTRA2 antibody) at dilution of 1:100 (under 10x lens)
  • 15775-1-AP;human kidneyImmunohistochemical of paraffin-embedded human kidney using 15775-1-AP(HTRA2 antibody) at dilution of 1:100 (under 40x lens)
  • 15775-1-AP;Raji cellsIP Result of anti-HTRA2 (IP:15775-1-AP, 4ug; Detection:15775-1-AP 1:500) with Raji cells lysate 2000ug.
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information HTRA2 抗体
Immunogen: HTRA2 fusion protein ag8455 Full Name: HtrA serine peptidase 2
Caculated Molecular
Weight:		 49 kDa Observed Molecular 
Weight:		 36 kDa
GenbankNo BC000096 GeneID: 27429
Symbol HTRA2 Synonyms HtrA serine peptidase 2, HTRA2, OMI, PARK13, PRSS25, Serine protease 25, Serine proteinase OMI
Background

HTRA2(High temperature requirement protein A2) is also named as OMI, PRSS25 and belongs to the peptidase S1B family. HTRA2 normally exists in the mitochondria, can cause MMP3 activation in the cytosol under a cell stress condition, which can ultimately lead to demise of dopaminergic neuronal cells(PMID: 22265821). It inhibits mitochondrial superoxide generation, stabilizes mitochondrial membrane potential, and prevents apoptosis at baseline and in response to extracellular inducers of mitochondrial stress(PMID: 18772386). This protein has 4 isoforms produced by alternative splicing. HTRA2 抗体

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