ITPKC抗体-抗体-抗体-生物在线
ITPKC抗体

ITPKC抗体

商家询价

产品名称： ITPKC抗体

英文名称： ITPKCAntibody

产品编号： XY 14267-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 ITPKC抗体

Applications
In-house applications ELISA, WB, IF, IHC, IP     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
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  • 14267-1-AP;human heart tissuehuman heart tissue were subjected to SDS PAGE followed by western blot with 14267-1-AP(ITPKC antibody) at dilution of 1:400
  • 14267-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using ITPKC antibody 14267-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
  • 14267-1-AP;HepG2 cellsIP Result of anti-ITPKC (IP:14267-1-AP, 4ug; Detection:14267-1-AP 1:400) with HepG2 cells lysate 1600ug.
  • 14267-1-AP;human skeletal muscle tissueImmunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using 14267-1-AP( ITPKC Antibody) at dilution of 1:50 (under 10x lens)
  • 14267-1-AP;human skeletal muscle tissueImmunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using 14267-1-AP( ITPKC Antibody) at dilution of 1:50 (under 40x lens)
Positive WB detected in Human heart tissue
Positive IP detected in HepG2 cells
Positive IHC detected in Human skeletal muscle tissue, human heart tissue, human lymphoma tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200
 ITPKC抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information ITPKC抗体
Immunogen ITPKC fusion protein ag5583 Full name Inositol 1,4,5-trisphosphate 3-kinase C
Calculated molecular
weight		 75 kDa Observed molecular 
weight		 100-105 kDa
GenBank accession 
number		 BC060788 Gene ID (NCBI) 80271
Gene symbol ITPKC Synonyms InsP 3 kinase C, IP3 3 kinase C, IP3K C, IP3KC, ITPKC
Background

ITPKC(Inositol-trisphosphate 3-kinase C) is also named as IP3KC and belongs to the inositol phosphokinase (IPK) family. It can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate and is relatively weakly activated by the calcium-calmodulin complex. ITPKC also acts as a negative regulator of T-cell activation through the Ca(2+)/NFAT signaling pathway, and the C allele may contribute to immune hyperreactivity in Kawasaki disease(PMID:17160344). ITPKC抗体

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