NHLRC3,非霍奇金淋巴瘤重复蛋白3抗体

产品编号HZ-9333R
英文名称NHLRC3
中文名称非霍奇金淋巴瘤重复蛋白3抗体
别 名DKFZp313M1221; DKFZp686E1140; NHL repeat containing 3; NHL repeat containing protein 3; NHLRC 3; NHLC3_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Sheep,
NHLRC3,非霍奇金淋巴瘤重复蛋白3抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量35kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human NHLRC3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
NHLRC3,非霍奇金淋巴瘤重复蛋白3抗体PubMedPubMed
产品介绍background:
NHLRC3 contains 4 NHL repeats. The function of the NHLRC3 protein remains unknown. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Subcellular Location:
Secreted

Similarity:
Contains 4 NHL repeats.

Gene ID:
387921

Database links:
Entrez Gene: 387921 Human
Entrez Gene: 212114 Mouse
Entrez Gene: 310416 Rat
SwissProt: Q5JS37 Human
SwissProt: Q8CCH2 Mouse
Unigene: 507783 Human
Unigene: 85744 Mouse

NHLRC3,非霍奇金淋巴瘤重复蛋白3抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.