FITC标记的磷脂合成酶1抗体
产品名称： FITC标记的磷脂合成酶1抗体
英文名称： Anti-PTDSS1/FITC
产品编号： HZ-19583R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PTDSS1/FITC Conjugated antibody
FITC标记的磷脂合成酶1抗体
| 英文名称Anti-PTDSS1/FITC中文名称FITC标记的磷脂合成酶1抗体别 名Phosphatidylserine synthase 1; PSS1; PSSA; PTSS1_HUMAN; PtdSer synthase 1; Serine exchange enzyme I. 规格价格100ul/2980元 购买 大包装/询价说 明 书100ul 研究领域肿瘤 细胞生物 信号转导 抗体来源Rabbit克隆类型Polyclonal交叉反应Human, Mouse, Rat, Pig, Cow, Horse, Sheep, 产品应用ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.分 子 量55kDa性 状Lyophilized or Liquid浓 度1mg/ml免 疫 原KLH conjugated synthetic peptide derived from human PTDSS1亚 型IgG纯化方法affinity purified by Protein A储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.产品介绍background: The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014] Function: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine. Subcellular Location: Membrane; Multi pass membrane protein. DISEASE: The disease is caused by mutations affecting the gene represented in this entry. Disease description:A syndrome of intellectual disability and multiple congenital anomalies that features generalized craniotubular hyperostosis. LMHD is characterized by the combination of sclerosing bone dysplasia, intellectual disability and distinct craniofacial, dental, cutaneous and distal limb anomalies. The progressive generalized hyperostosis associated with this syndrome affects the cranium, the vertebrae and the diaphyses of tubular bones, leading to severe growth restriction Similarity: Belongs to the phosphatidyl serine synthase family. Database links: Entrez Gene: 9791 Human Entrez Gene: 19210 Mouse Entrez Gene: 314553 Rat Omim: 612792 Human SwissProt: P48651 Human SwissProt: Q99LH2 Mouse Unigene: 292579 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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该基因编码的蛋白质催化磷脂酰胆碱或磷脂酰乙醇胺形成磷脂酰丝氨酸。磷脂酰丝氨酸定位于内质网的线粒体相关膜，在那里它起着结构作用和信号作用。这一基因的缺陷是Lenz Majewski高渗性侏儒症的原因之一。发现了两个编码不同亚型的转录变体。〔RefSeq，2014〕