DGCR2,DGCR2蛋白抗体

产品编号HZ-8258R
英文名称DGCR2
中文名称DGCR2蛋白抗体
别 名DGS C; DGS2; DiGeorge syndrome critical region gene 2; IDD; integral membrane protein DGCR2; LAN; SEZ 12.
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 免疫学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow, Rabbit, Zebrafish, xenopuslaevisorangutan
DGCR2,DGCR2蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量59kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DGCR2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DGCR2,DGCR2蛋白抗体PubMedPubMed
产品介绍background:
The DGCR2 gene encodes a novel putative adhesion receptor protein, which may play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22.

Function:
Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.

Subcellular Location:
Membrane; Single pass type I membrane protein.

Tissue Specificity:
Predominantly expressed in brain, heart, lung and fetal kidney. Low levels in liver and adult kidney.

Similarity:
Contains 1 C-type lectin domain.
Contains 1 LDL-receptor class A domain.
Contains 1 VWFC domain.

Database links:
UniProtKB/Swiss-Prot: P98153.1

DGCR2,DGCR2蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.