KIF5B/RET DY Translocation FISH Probe-核酸检测-试剂-生物在线
KIF5B/RET DY Translocation FISH Probe

KIF5B/RET DY Translocation FISH Probe

商家询价

产品名称： KIF5B/RET DY Translocation FISH Probe

英文名称： KIF5B/RET DY Translocation FISH Probe

产品编号： FT0007

产品价格： 0

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围： null

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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology)
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FT0007
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Note:
  • Hybridization position of the probes on the chromosome:

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • KIF5B
    Approximately 1370kb
    FITC
    10p11.2
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • RET
    Approximately 1180kb
    Texas Red
    10q11.2
  • Probe Gap:
  • The gap between two probes is approximately 10,000 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human lung adenosquamous cell carcinoma (FFPE) stained with KIF5B/RET DY Translocation FISH Probe . Human lung adenosquamous cell carcinoma showed KIF5B/RET DY translocation.
  • Protocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3799
  • Gene Name:
  • KIF5B
  • Gene Alias:
  • KINH,KNS,KNS1,UKHC
  • Gene Description:
  • kinesin family member 5B
  • Other Designations:
  • kinesin 1 (110-120kD),kinesin heavy chain
  • Gene Information
  • Entrez GeneID:
  • 5979
  • Gene Name:
  • RET
  • Gene Alias:
  • CDHF12,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET-ELE1,RET51
  • Gene Description:
  • ret proto-oncogene
  • Gene Summary:
  • This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq
  • Other Designations:
  • RET transforming sequence,cadherin family member 12,hydroxyaryl-protein kinase,oncogene RET,receptor tyrosine kinase,ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)

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