Anti-SCIN/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-SCIN/FITC Conjugated抗体

Anti-SCIN/FITC Conjugated抗体

商家询价

产品名称: Anti-SCIN/FITC Conjugated抗体

英文名称: Anti-SCIN/FITC

产品编号: YB--17286R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-SCIN/FITC Conjugated抗体

产品编号 YB-17286R-FITC
英文名称 Anti-SCIN/FITC
中文名称 FITC标记的肌切蛋白抗体
别    名 Adseverin; KIAA1905; ADSV_HUMAN; Scinderin.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCIN
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SCIN (Scinderin) is a Ca(2+) dependent actin filament severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro SCIN also has barbed end capping and nucleating activities in the presence of Ca(2+).

Function:
Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).

Subcellular Location:
Cytoplasmic, cytoskeleton.

Similarity:
Belongs to the villin/gelsolin family. 
Contains 6 gelsolin-like repeats. 

Database links:

Entrez Gene: 85477 Human

Omim: 613416 Human

SwissProt: Q9Y6U3 Human

SwissProt: D4A2G2 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications