OCT4 Rabbit pAb (APR27816N)-抗体-抗体-生物在线
OCT4 Rabbit pAb (APR27816N)

OCT4 Rabbit pAb (APR27816N)

商家询价

产品名称: OCT4 Rabbit pAb (APR27816N)

英文名称: OCT4 Rabbit pAb (APR27816N)

产品编号: APR27816N

产品价格: null

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: IHC (HeLa cells, Homo sapiens, Mus musculus) IF (HeLa cells) WB (Homo sapiens, Mus musculus)

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  • 所在区域 : 上海
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分子量:Calculated MW: 30kDa/38kDa
Observed MW: 45KDa

细胞定位:Cytoplasm, Nucleus

稀释方法:WB 1:500 - 1:2000
IHC 1:50 - 1:200

总结:This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.