分子量:46.8 kDa

纯度:>90% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human OX40, Fc Tag by the LAL method.

Buffer:50 mM tris, 100 mM glycine, pH7.5

生物活性:Measured by its binding ability in a functional ELISA.ImmobilizedHuman OX40 Ligand, His Tag (Cat# OXL-H52Q8) at 5 μg/mL (100 μl/well) can bind Human OX40, Fc Tag (Cat# OX0-H5255 ) with a linear range of  0.2-5 ng/mL.


产品特性:Human OX40, Fc Tag is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 46.8 kDa. The predicted N-terminus is Leu 29. The reducing (R) protein migrates as 65 kDa in SDS-PAGE  due to glycosylation.

产品背景:Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.