FITC标记的环指蛋白14抗体
产品名称： FITC标记的环指蛋白14抗体
英文名称： Anti-RNF14/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-RNF14/FITC Conjugated antibody
FITC标记的环指蛋白14抗体
| 产品编号 | bs-9225R-FITC |
| 英文名称 | Anti-RNF14/FITC |
| 中文名称 | FITC标记的环指蛋白14抗体 |
| 别 名 | Androgen receptor associated protein 54; Androgen receptor-associated protein 54; ARA 54; ARA54; E3 ubiquitin protein ligase RNF14; E3 ubiquitin-protein ligase RNF14; FLJ26004; HFB 30; HFB30; HRIHFB2038; RING finger protein 14; RNF 14; Rnf14; RNF14_HUMAN; TRIAD 2; TRIAD2; Triad2 protein. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RNF14 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription. Function: Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription. Subunit: Interacts with the ubiquitin-conjugating enzymes UBE2E1 and UBE2E2. Interacts with AR/androgen receptor; testosterone- and RNF6-regulated it promotes AR transcriptional activity. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Widely expressed. Post-translational modifications: RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination. [SIMILARITY] Similarity: Belongs to the RBR family. RNF14 subfamily. Contains 1 IBR-type zinc finger. Contains 2 RING-type zinc fingers. Contains 1 RWD domain. Database links: Entrez Gene: 9604 Human Entrez Gene: 56736 Mouse Entrez Gene: 619577 Rat Omim: 605675 Human SwissProt: Q9UBS8 Human SwissProt: Q9JI90 Mouse Unigene: 483616 Human Unigene: 228903 Mouse Unigene: 115357 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
可能作为E3泛素蛋白连接酶，接受来自特定E2泛素缀合酶的泛素，然后将其转移到底物，其可以是核蛋白。可以起到雄的辅激活作用，并且在较小程度上依赖于孕依赖的转录。