PCDHGA7,原钙粘蛋白γA7抗体

产品编号HZ-11148R
英文名称PCDHGA7
中文名称原钙粘蛋白γA7抗体
别 名PCDG7_HUMAN; PCDH-gamma-A7; PCDHGA7; protocadherin gamma subfamily A, 7; Protocadherin gamma-A7.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat,
PCDHGA7,原钙粘蛋白γA7抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量99kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human PCDHGA7
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PCDHGA7,原钙粘蛋白γA7抗体PubMedPubMed
产品介绍background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGA7 (Protocadherin gamma-A7) is a 932 amino acid that is one of 22 proteins encoded by the protocadherin gamma cluster. The protocadherein gamma cluster consists of three subfamilies (A, B and C) and PCDHGA7 is a member of the gamma subfamily A. PCDHGA7 is a type I transmembrane receptor containing six cadherin motifs and is expressed in the central nervous system where it localizes to synapses. Members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGA7 that are produced as a result of alternative splicing events.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein

Similarity:
Contains 6 cadherin domains.

Gene ID:
Swiss-Prot: Q9Y5G6.1

Database links:
UniProtKB/Swiss-Prot: Q9Y5G6.1

PCDHGA7,原钙粘蛋白γA7抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.