Anti-p38 MAPK Monoclonal Antibody
产品名称: Anti-p38 MAPK Monoclonal Antibody
英文名称: Anti-p38 MAPK Monoclonal Antibody
产品编号: K000093M
产品价格: 0
产品产地: 北京
品牌商标: Solarbio
更新时间: 2024-04-30T09:30:02
使用范围: null
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073
- 传真 :
- 邮箱 : 3193328036@qq.com
Anti-p38 MAPK Monoclonal Antibody
品牌:Solarbio | 货号:K000093M
英文名称 | Mouse p38 MAPK Monoclonal Antibody |
---|---|
应用2 | WB |
克隆类型2 | Monoclonal Antibody |
别名 | p38 MAPK |
应用 | WB |
稀释比例 | WB1:500 |
交叉反应 | Human Mouse Rat Monkey |
蛋白分子量 | 40kDa |
Gene ID | 1432 |
保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 72% Glycerol. |
纯化方法 | Affinity purification |
亚型 | IgG1 |
免疫原 | Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli. |
性状 | Lyophilized or Liquid |
Swiss Prot | Q16539 |
克隆号 | 5A1-C5-F11 |
克隆类型 | Monoclonal Antibody |
来源 | Mouse |
背景资料 | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |