TEL/AML1,DY Translocation FISH Probe
产品名称： TEL/AML1,DY Translocation FISH Probe
英文名称： TEL/AML1,DY Translocation FISH Probe
产品编号： FA0643
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL) 250 uL
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Entrez GeneID:
- 2120
- Gene Name:
- ETV6
- Gene Alias:
- TEL,TEL/ABL
- Gene Description:
- ets variant 6
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq
- Other Designations:
- TEL oncogene,TEL1 oncogene,ets variant gene 6 (TEL oncogene)
- Entrez GeneID:
- 861
- Gene Name:
- RUNX1
- Gene Alias:
- AML1,AML1-EVI-1,AMLCR1,CBFA2,EVI-1,PEBP2aB
- Gene Description:
- runt-related transcription factor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- AML1-EVI-1 fusion protein,acute myeloid leukemia 1,aml1 oncogene,core-binding factor, runt domain, alpha subunit 2