Size  100ug
Cat code  200725
Species Cross-reactivity  H
Key Application  WB,ICC
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG1
Molecular Weight  36kDa
Sensitivity  This antibody detects endogenous levels of AKR1B1 and does not cross-react with related proteins.
Immunogen  Purified recombinant human AKR1B1 protein fragments expressed in E.coli.
UniProt Number  P15121
GeneBank ID  NM_001628.2
Subcellular location  Cytoplasm
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  ALDR1;AR;Aldo-keto reductase family 1 member B1;ADR;ALR2;Lii5-2 CTCL tumor antigen;Aldehyde reductase
Gene_symbol  AR; ADR; ALR2; ALDR1 
Summary  This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database
UniPort summary  Function  Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Application Images :  
Western blot detection of AKR1B1 in HT1080,MCF7,A431&Hela cell lysates using AKR1B1 antibody (1:1000 diluted).
Predicted band size:36KDa.
Observed band size:36KDa