人参皂苷Ra3
产品名称： 人参皂苷Ra3
英文名称： Ginsenoside Ra3
产品编号： 90985-77-6
产品价格： 0
产品产地： 吉林长春
品牌商标： 星海金森
更新时间： null
使用范围： null
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- 地址 : 常熟高新技术产业开发区湖山路333号同济科技广场
- 邮编 :
- 所在区域 : 江苏
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- 邮箱 : sales@star-ocean-biotech.com;star-ocean@vip.163.com
Ginsenoside Ra3 Biological Activity
IC50 Value & Target:
In Vitro: Plasma 20(S)-protopanaxadiol and 20(S)-protopanaxatriol could be used as pharmacokinetic markers to reflect the subjects microbial activities, as well as the timely-changes and interindividual differences in plasma levels of their respective oxidized metabolites. [2].
In Vivo: After ingestion of Sanchi extract, ginsenosides Ra3, Rb1, Rd, Rg1, F1, Rh1, and notoginsenoside R1 were measured in plasma samples. Deglycosylated metabolites Compound-K, protopanaxadiol, and protopanaxatriol were also detected in plasma. Notably, several metabolites of protopanaxadiol and protopanaxatriol were found in human plasma and characterized, the plasma concentrations of which were significantly higher than those of the circulating ginsenosides. Conclusion: Although the ginsenoside aglycones protopanaxadiol and protopanaxatriol were not contained in the test Sanqi extract, their oxidized metabolites represented a class of major circulating compounds after ingestion of the herbal extract to humans. [1]. The PK profiles of the Sanqi ginsenosides in humans were comparable to those found in rats. Slight interspecies differences could have been due to humans being relatively poor biliary excretors compared with rats.[3].
  | Dave Gao Sales Manager, Star Ocean Ginseng Professional Services Tel: +86 512 81662860 Mobile: +86 13776237441 Fax: +86 512 52856900 Address: High Tech Industrial Development Zone-Tongji Science and Technology Plaza, Changshu, Suzhou, China. |