PeproTech重组人IGF Binding Protein-5 5ug-细胞/细菌培养-试剂-生物在线
PeproTech重组人IGF Binding Protein-5 5ug

PeproTech重组人IGF Binding Protein-5 5ug

商家询价

产品名称: PeproTech重组人IGF Binding Protein-5 5ug

英文名称: Recombinant Human IGF Binding Protein-5

产品编号: 100-05

产品价格: 0

产品产地: 美国

品牌商标: PeproTech

更新时间: null

使用范围: null

美国PeproTech(派普泰克)公司中国代表处
  • 联系人 :
  • 地址 :  江苏省苏州市工业园区星湖街218号A1北座4楼L03
  • 邮编 : 215123
  • 所在区域 : 江苏
  • 电话 :
  • 传真 : 0512-68325993
  • 邮箱 : peprotech.infochina@thermofisher.com

 

Human Growth Factors & Cytokines

Recombinant Human IGF-BP5



 

Synonyms :

Insulin-like Growth Factor-Binding Protein5

Description :

IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.

Catalog #:

100-05

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is ≤ 0.3 μg/ml in the presence of 15 ng/ml of human IGF-II.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS

PubMed Link :

IGF Binding Protein 5

Country of Origin :

USA


Size A 5μg $80   
 
Size B 25μg $195   
 
Size C 1mg $3000   
 


Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.

Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.