Human Growth Factors & Cytokines
Recombinant Human FGF-8





 





		Synonyms :
Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF



		Description :
FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family.  Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.  There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F.  The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical.  FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors.  Recombinant human FGF-8 (FGF-8b) is a 22.4 kDa protein consisting of 193 amino acid residues.



		Catalog #:
100-25



		Source :
E.coli



		Purity :
Greater than 95% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR 



		PubMed Link :
FGF-8


Country of Origin :
USA
















        Size A
5μg
$80 
 


 



        Size B
25μg
$195 
 


 



        Size C
1mg
$3000 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.