Human Growth Factors & Cytokines
Recombinant Human IL-19





 





		Synonyms :
Melanoma differentiation association like protein



		Description :
IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26.  Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions.  Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α.  IL-19 signals through the type I IL-20R.  Human and murine IL-19 share 71% amino acid sequence identity.  Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues.  In solution IL-19 exists predominantly as a non-disulfide-linked dimer.



		Catalog #:
200-19



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability to activate STAT following receptor-ligand interaction.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MSSA 



		PubMed Link :
IL-19+AND+human


Country of Origin :
USA
















        Size A
2μg
$80 
 


 



        Size B
10μg
$195 
 


 



        Size C
1mg
$5200 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.