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         ScienCell研究实验室生产的原代细胞、原代细胞专用培养基都经过了严格的质量控制，细胞纯度可达98％。其中包括21种人体正常细胞系统，90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离，产品质量过硬。确保了实验结果的重复性和连贯性。
 
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产品：人精囊成纤维细胞

货号：4470

Description

Seminal vesicles (SV) are a pair of tubular glands located near theprostate and are essential to the urinary system. They function underandrogen control to produce and secrete fluid into the ejaculatory duct.SV consists of three layers: the inner basal mucosal layer composed ofsimple cuboidal and pseudo-stratified columnar epithelial cells, themiddle muscular layer formed by smooth muscle cells, and the outer layermade up of dense connective tissue. Various pathological conditions canarise in the SV, including congenital SV cysts, seminal vesculitis, andprimary and secondary neoplasms [1-3]. Additionally, seminal vesicleinvasion is often used as a prognostic marker in prostate cancer [4]. SVfibroblasts offer unique opportunities to study many features of the SV.

HSVF from ScienCell Research Laboratories are isolated from humanseminal vesicle tissue. HSVF are cryopreserved at passage one anddelivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume.HSVF are characterized by their spindle morphology andimmunofluorescence with antibody specific to fibronectin. HSVF arenegative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi.HSVF are guaranteed to further expand for 15 population doublings underthe conditions provided by ScienCell Research Laboratories.


Recommended Medium

It is recommended to use Fibroblast Medium (FM, Cat. #2301) for theculturing of HSVF in vitro.


Product Use

HSVF are for research use only. It is not approved for human or animaluse, or for application in in vitro diagnostic procedures.


Storage

Directly and immediately transfer cells from dry ice to liquid nitrogenupon receiving and keep the cells in liquid nitrogen until cell cultureis needed for experiments.


Shipping

Dry ice.


Reference

[1] Arora SS, Breiman RS, Webb EM, Westphalen AC, Yeh BM, Coakley FV.(2007) “CT and MRI of congenital anomalies of the seminal vesicles.” AJRAm J Roentgenol. 189: 130-5.
[2] Campobasso D, Fornia S, Ferretti S, Maestroni U, Cortellini P.(2012) “Primary bilateral seminal vesicle carcinoma: description of acase and literature review.” Int J Surg Pathol. 20: 633-5.
[3] Wang J, Yue X, Zhao R, Cheng B, Wazir R, Wang K. (2013) “Primarysquamous cell carcinoma of seminal vesicle: an extremely rare casereport with literature review.” Int Urol Nephrol. 45: 135-8.
[4] Kristiansen A, Wiklund F, Wiklund P, Egevad L. (2013) “Prognosticsignificance of patterns of seminal vesicle invasion in prostatecancer.” Histopathology. 62: 1049-56.