Biotinylated Human TNF-alpha, epitope tag free, ultra sensitivity (primary amine labeling)北京百普赛斯生物科技有限公司

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产品名称: Biotinylated Human TNF-alpha, epitope tag free, ultra sensitivity (primary amine labeling)
英文名称: Biotinylated Human TNF-alpha, epitope tag free, ultra sensitivity (primary amine labeling)
产品货号: TNA-H8211
产品规格: 200ug
试剂级别: 试剂级
产品产地: USA
产品商标: ACROBiosystems
价    格: 12500元
保存与运输: 保存:-20℃运输:粉末,常温
现货状态: 现货
产品资料: 实验方法技术资料
更新时间: 2017-9-8 11:07:00
浏览人数:788
诚信指数:467点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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供应商联系卡

北京百普赛斯生物科技有限公司
地址:
北京经济技术开发区宏达北路8号5号楼4层
邮编:
100176
电话:
400-682-2521
传真:
010-58043677
联系人:
占女士
所在区域:
北京·北京
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产品详细描述

分子量:40.4 kDa

纯度:>95% as determined by SDS-PAGE and more than 90% measured by SEC-HPLC.

内毒素:Less than 1.0 EU per μg of the Human CD47, Fc Tag (HPLC-verified) by the LAL method.

Buffer:50 mM tris, 100 mM glycine, pH7.5

生物活性:Measured by its binding ability in a functional ELISA. Immobilized Human CD47, Fc Tag (HPLC-verified) (Catalog # CD7-H5256) at 2 μg/mL  can bind  Human SIRP alpha, His Tag (Catalog # SIA-H5225) with a linear range of 16-250 ng/mL.

产品特性:Human CD47, Fc Tag (HPLC-verified) is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 40.4 kDa. The predicted N-terminus is Gln 19. The reducing (R) protein migrates as 50-65 kDa in SDS-PAGE  due to glycosylation.

产品背景:Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. 
SDS-PAGE

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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