分子量:16.8 kDa

纯度:>92% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human CD69, His Tag by the LAL method.

Buffer:PBS, pH7.4

生物活性:

产品特性:Human CD69, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 16.8 kDa. The predicted N-terminus is Ser 62. The reducing (R) protein migrates as 23 kDa and 26 kDa in SDS-PAGE  due to different glycosylation.

产品背景:Early activation antigen CD69 is also known as C-type lectin domain family 2 member C (CLEC2C), Activation inducer molecule (AIM), Early T-cell activation antigen p60, Leukocyte surface antigen Leu-23. CD69 contains one C-type lectin domain. CD69 / CLEC2C is expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. CD69 is induced by antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes and by interaction of IL-2 with the p75 IL-2R on the surface of NK cells. CD69 / CLEC2C involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.