Human CD96 / TACTILE Protein, His Tag北京百普赛斯生物科技有限公司

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产品名称: Human CD96 / TACTILE Protein, His Tag
英文名称: Human CD96 / TACTILE Protein, His Tag
产品货号: TAE-H52H0
产品规格: 100ug,1mg
产品产地: USA
产品商标: ACROBiosystems
价    格: 3500,23100元
保存与运输: -20
产品资料: 实验方法技术资料
更新时间: 2017-12-5 14:33:00
浏览人数:7
诚信指数:475点
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使用范围:仅限科研使用,不能应用于临床
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供应商联系卡

北京百普赛斯生物科技有限公司
地址:
北京经济技术开发区宏达北路8号5号楼4层
邮编:
100176
电话:
400-682-2521
传真:
010-58043677
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占女士
所在区域:
北京·北京
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产品详细描述

 

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>90% as determined by SDS-PAGE.

活性:
Immobilized Human CD155, Fc Tag (Cat. No. CD5-H5251) at 20 μg/mL (100 μL/well) can bind Human CD96, His Tag (Cat. No. TAE-H52H0) with a linear range of 1.25-20 μg/mL (QC tested).

产品背景:
The progression of pancreatic cancer (PC) is significantly associated with tumor immune escape, which may be associated with nature killer (NK) cell dysfunction. CD226, CD96, and TIGIT, which share the ligand CD155, play important roles in the regulation of NK cell function. The present study was conducted to investigate the roles of these molecules in NK cells from PC patients. TIGIT and CD96 together with the co-stimulatory receptor CD226 form a pathway that is analogous to the CD28/CTLA-4 pathway, in which shared ligands and differential receptor:ligand affinities fine-tune the immune response. Although the roles of TIGIT and CD96 as immune checkpoint receptors in T cell and natural killer cell biology are just beginning to be uncovered, accumulating data support the targeting of these receptors for improving anti-tumor immune responses. A clear understanding of the immune cell populations regulated by TIGIT and CD96 is key to the design of immunotherapies that target these receptors in combination with other existing immune checkpoint blockade therapies. The dysfunction of CD96 may trigger C syndrome: A syndrome characterized by trigonocephaly, severe mental retardation, hypotonia, variable cardiac defects, redundant skin, and dysmorphic facial features, including upslanted palpebral fissures, epicanthal folds, depressed nasal bridge, and low-set, posteriorly rotated ears.

产品描述:
Human CD96, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

SDS-PAGE


 

因为难以在供应系统上进行数据同步,所以了解更多产品规格及产品数据,请移步:

http://www.acrobiosystems.cn/P1155-Human_CD96_%7C_TACTILE_Protein_His_Tag.html

订购方式
您可以通过官网查看产品信息、拨打订购电话、发送邮件或者直接点索取报价等方式进行订购,我们的客服将会竭诚为您服务。
电话:400-682-2521  
网址:http://www.acrobiosystems.cn
邮箱:order.cn@acrobiosystems.com(订购及产品咨询)

邮箱:techsupport@acrobiosystems.com(技术支持)(请咨询时注明是在丁香通看到产品信息)

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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