Murine & Rat Growth Factors & Cytokines
            
Recombinant Rat GM-CSF
            

            

             
        
        

            
 
            

            

                

                    

                        

                        
Synonyms :
                        
                        

                        
Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
                        
                    
                    

                        

                        
Description :
                        
                        

                        
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues.
                        
                    
                    

                        

                        
Catalog #:
                        
                        

                        
400-23
                        
                    
                    

                        

                        
Source :
                        
                        

                        
E.coli
                        
                    
                    

                        

                        
Purity :
                        
                        

                        
Greater than 98% by SDS-PAGE gel and HPLC analyses.
                        
                    
                    

                        

                        
Endotoxin Level :
                        
                        

                        
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
                        
                    
                    

                        

                        
Biological Activity :
                        
                        

                        
The ED50 was determined by the dose-dependent stimulation of the proliferation of Murine FDC-P1 cells is < 0.01 ng/ml, corresponding to a specific activity of > 1.0 x 108 units/mg.
                        
                    
                    

                        

                        
Selected References :
                        
                        

                        
Selected List of References Citing This PeproTech Product
                        
                    
                    

                        

                        
AA Sequence :
                        
                        

                        
MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK 
                        
                    
                    

                        

                        
PubMed Link :
                        
                        

                        
GM-CSF+AND+rat
                        
                    
                    

                        

                        
Country of Origin :
                        
                        

                        
USA
                        
                    
                    

                        
 
                        

                        
                    
                    

                        

                        
 
                        
                        

                        

                        

                            

                                

                                    
Size A
                                    
5μg
                                    
$80 
                                    
 
                                
                                

                                    
 
                                
                                

                                    
Size B
                                    
20μg
                                    
$195 
                                    
 
                                
                                

                                    
 
                                
                                

                                    
Size C
                                    
1mg
                                    
$3250 
                                    
 
                                
                                

                                    
 
                                
                            
                        
                        

                        
                    
                    

                        

                        
 
                        
                        

                        
                    
                    

                        

                        
 
                        
                        

                        
Special Sizes: 

                        Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.
                        
                    
                    

                        

                        
 
                        
                        

                        
Usage:

                        For Research Use Only. Not for use in diagnostic or therapeutic procedures.