目录号 
                        
规格 
                        
价格 
                        
说明书下载 
                    
                    

                        
C585A
                        
2μg
                        
400元
                        

                    
                    

                        
C585B
                        
10μg
                        
1800元
                    
                    

                        
C585C
                        
50μg
                        
4500元
                    
                
            
            
        
        

            

            
 
            
FHR1 (Complement Factor H-related protein 1), also known as FHR-1, H factor-like protein 1, H-factor-like 1 and H36, is a 43 kDa, secreted member of the factor H family of glycoproteins. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids (aa) in length. It contains five, approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation, lipid metabolism and lipoprotein complexes that bind PMNs to LPS.
            


            ·Description

            Novoprotein Recombinant Human Complement Factor H-related 1/CFHR1 produced by mammalian cells expression system.Target protein is expressed with sequence (Glu19-Arg330) of Human cfhr1 (Uniprot #Q03591) fused with a polyhistidine tag at the C-terminus.
            


            ·Quality Control
            
Purity: Greater than 90.0% as determined by: 

            (a) Analysis by RP-HPLC. 

            (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. 

             
            
Endotoxin:Less than 0.1ng/μg (1EU/μg) of Complement Factor H-related 1/CFHR1 (Human)
            
 
            
·Formulation

              Novoprotein Recombinant Human CFHR1 was lyophilized at 1mg/ml in 20mM PBS.
            
·Reconstitution

            We recommend a quick spin followed by reconstitution of Novoprotein Recombinant Human CFHR1 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to working solutions.
            
·Storage 

            Lyophilized Recombinant Human CFHR1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Recombinant Human CFHR1 should be stored at 4°C between 2-7 days and aliquots of reconstituted samples are stable up to 3 months below -18°C for future use.
            
 
            
Please avoid freeze-thaw cycles.