美国ScienCell研究实验室（www.sciencellonline.com）成立于1999年，公司总部位于美国加州的圣地亚哥。主要致力于实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养基的研究和开发，在全球拥有众多客户。在国内销售8年来，很多老师应用其产品发表了高质量的SCI文章，且有着极高的文献引用率。凭借着严格的质控和优秀的产品品质，深受广大科研工作者的信赖。
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    ScienCell研究实验室生产的原代细胞、原代细胞专用培养基都经过了严格的质量控制，细胞纯度可达98％。其中包括21种人体正常细胞系统，90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离，产品质量过硬。确保了实验结果的重复性和连贯性。

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人视网膜内皮细胞 说明：
货号：6530
 
眼部包含的富含血管和完全无血管的组织，并且紧紧排列的。这种特殊的解剖关系要求对血管的静止和生长平衡有严格的调控。视网膜的血管生成是各种血管细胞，如内皮细胞、外膜细胞、星状胶质细胞，各种正负调节因子产生平衡之间协调的相互作用。在血管生成相关的眼病中，这种微妙的平衡遭到破坏。在大部分致盲性疾病中，血管生成都有重要作用，如糖尿病视网膜病、早产儿视网膜病、老年黄斑退行性变，同时也与许多其它眼病有关。通过研究视网膜内皮细胞，人们越来越清楚了解早期的糖尿病视网膜病和其它的视网膜微血管病。利用人视网膜内皮细胞的培养，可以为我们研究眼血管疾病的病理生理改变提供体外模型。        人视网膜内皮细胞(HREC)提取于人视网膜组织，原代冻存。每管含有细胞数>5×10⁵ cells/ml，此细胞通过vWF/Factor VIII 和CD31 (P-CAM)免疫荧光染色验证，经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。

推荐培养基:(ECM, Cat. No. 1001)

The eye contains highly vascularised and completely avascular tissues in close apposition. This specialized anatomy requires tight regulation of the balance between vascular quiescence and vascular growth. Retinal vascularization is a coordinated interaction of vascular cells, including endothelial cells, pericytes, and astrocytes, and a balanced production of positive and negative regulatory factors [1]. In eye diseases associated with angiogenesis, this delicate balance is disturbed. Angiogenesis plays a crucial role in disorders responsible for most blindness such as diabetic retinopathy, retinopathy of prematurity, age-related macular degeneration, as well as a large number of other eye conditions. Studies of retinal capillary endothelial cells have shed lights on the earliest stages of diabetic retinopathy and other diseases of the retinal microvasculature [2, 3]. Human retinal endothelial cell cultures will surely continue to provide an in vitro model in the pathophysiological studies of vascular diseases in the human eye.
HREC from ScienCell Research Laboratories are isolated from human retinal tissue. HREC are cryopreserved on passage one and delivered frozen. Each vial contains >5 x 10⁵ cells in 1 ml volume. HREC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CD31 (P-CAM) and by uptake of DiI-Ac-LDL. HREC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HREC are guaranteed to further culture at the conditions provided by ScienCell Research Laboratories.

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