Recombinant Human DLC1 Protein
产品名称: Recombinant Human DLC1 Protein
英文名称: Recombinant Human DLC1 Protein
产品编号: RP-1821H
产品价格: 0
产品产地: 美国
品牌商标: AdvBiomart
更新时间: null
使用范围: null
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Deleted in Liver Cancer 1 (DLC1), also known as rho GTPase-activating protein 7 (ARHGAP7) and StAR-related lipid transfer protein 12 (STARD12). DLC1 gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. The DLC1 protein contains four major functional domains: an N-terminal sterile α motif (SAM), a serine-rich (SR) region, a Rho-GAP domain, and a C-terminal steroidogenic acute regulatory protein related lipid-transfer (START) domain.