Catalog Number:100-56A
Description:
PlGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-2 is expressed in umbilical vein endothelial cells and placenta. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. PlGF-2 also signals through Neuropilin (NP-1), and can bind with high affinity to heparin. Recombinant Human PlGF-2 is a 34.6 kDa disulfide-linked homodimeric protein of two 152 amino acid polypeptide chains.
Source:E.coli
Synonyms:Placenta Growth Factor-2, PGFL
AA Sequence (monomer):LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR
Purity:≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:Determined by its ability to chemoattract human THP-1 cells of using a concentration range of 5.0-50.0 ng/ml.
PubMed
SDS
Product Line
Country Of Origin: USA
Not for human use.