Hydroxychloroquine | 羟氯喹
MCE 国际站：Hydroxychloroquine
中文名：羟氯喹
CAS：118-42-3
品牌：MedChemExpress (MCE)
存储条件：Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性：羟氯喹是一种合成的抗疟剂，它还可以抑制Toll 样受体 7/9 (TLR7/9) 信号传导。羟氯喹在体外有效抑制SARS-CoV-2感染[1][2][3]。
热销产品：Uric acid | Bufalin | Deoxynivalenol | 7,4'-Dihydroxyflavone | Sal003 | Sodium oleate | D-Glucose 6-phosphate | Hypoxanthine | ML-180 | Digoxigenin monodigitoxoside
研究领域：Anti-infection | Immunology/Inflammation | Autophagy
作用靶点：Parasite | Toll-like Receptor (TLR) | SARS-CoV | Autophagy
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献：
[1]. Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6.[2]. Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40.[3]. Yao X, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020 Mar 9. pii: ciaa237.